Comparing injection devices

A comparison of disease-modifying MS therapy injection devices

Feature RebiSmart™
from EMD Serono Canada Inc.

For use with:
Rebif® (interferon beta-1a)
Rebiject II™
from EMD Serono Canada Inc.

For use with:
Rebif® 
(interferon beta-1a)
Betaject® Lite
from Bayer Inc.

For use with:
Betaseron® 
(interferon beta-1b)
Betaject® Comfort
from Bayer Inc.

For use with:
Betaseron® (interferon beta-1b)
Personal Injector™
from Union Medico (licensed by Biogen Idec)

For use with: Avonex® 
(interferon beta-1a)
Autoject® 2
from Teva Pharmaceutical Industries Ltd.

For use with:
Copaxone®
(glatiramer acetate)
Disposable Syringe/Needle
available from all manufacturers

Available for each disease-modifying drug product
Autoinjector Automatic electronic injection at the press of a button
Automatic injection at the press of a button
Automatic injection at the press of a button
Automatic injection at the press of a button
Automatic injection at the press of a button
Automatic injection at the press of a button
N/A
On-screen multilingual instructions Information and interactive instructions available in 26 languages help simplify and guide you through the injection process
N/A N/A N/A N/A N/A N/A
Preset titration doses/ schedule (for therapy initiation) Dose is easily preset by healthcare professional; can make therapy initiation easier for user 
User is provided a therapy initiation pack for the titration period No therapy titration pack; user must follow healthcare professional instructions and adjust dosage during therapy intiation period No therapy titration pack; user must follow healthcare professional instructions and adjust dosage during therapy intiation period No therapy titration pack; user must follow healthcare professional instructions and adjust dosage during therapy intiation period N/A (titration of the initial dose is not necessary) Dependent on disease-modifying drug product
Adjustable injection settings  Maximize injection comfort with adjustable needle speed, injection speed, injection time and needle depth10 mm
Adjustable needle depth only Adjustable needle depth only Adjustable needle depth only Manually adjustable
Adjustable needle depth only Manually adjustable
Dose log/ memory Records date, time and number of all previous injections to individualize injection schedule
N/A N/A N/A N/A N/A N/A
Needle

(gauge [G]*) *The higher the gauge, the thinner the needle 
Hidden before, during and after injection

Two needle size options:
29G and 30G
Hidden before and during injection

Needle size:
29G
Hidden only before and during injection

Needle size:
30G
Hidden before, during and after injection

Needle size:
30G
Exposed during entire administration process

Two needle size options:
23G and 25G
Hidden before, during and after injection

Needle size:
29G
Exposed during entire administration process

Needle size:
dependent on disease-modifying drug product


RebiSmart™ and Rebiject II™ are trademarks of EMD Serono Canada Inc.
Betaject® Lite, and Betaject® Comfort are registered trademarks of Bayer Inc.
Personal Injector™ is a trademark of Union Medico.
Autoject® 2 is a registered trademark of Teva Pharmaceutical Industries Ltd.

At no time should the information presented replace or supersede the recommendations of your own physician.  If you have any concerns, please take the information or questions to your physician.